Beilstein J. Org. Chem.2016,12, 2823–2827, doi:10.3762/bjoc.12.281
each other in a cyclohexane ring is introduced as a new design strategy which could be applicable to the preparation of polar hydrophobic cyclohexane motifs.
Keywords: aliphaticrings; C–F bond; cyclohexane conformation; difluoromethylene group; organofluorine chemistry; Introduction
Selective
Beilstein J. Org. Chem.2015,11, 481–492, doi:10.3762/bjoc.11.54
slightly bent orientation to each other, with the 7-membered ring in the same curved line. The 5-membered tetrahydrofuryl ring is disposed orthogonally to the curved backbone and is in a puckered conformation, typical of 5-membered aliphaticrings. The heterocycle is stable at room temperature and to air
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Graphical Abstract
Scheme 1:
The synthesis of N-monoallylated indigo derivatives.